There are lots of great new bikes out that are in the class of the Speedy. My 2 cents is try them all for test rides as long as they will let you. Changing bikes is expensive due to the immediate depreciation of a new bike so you want to be sure and confident with your decision.
I also sense you are ready for something new which makes sense. Maybe sell the cbr and keep the daytona for sport bike rides.
Also, remember the saying "too many bikes so little time" or something like that :)
I have tried BMW S1000R, Yamaha MT-10, Aprilia Tuono 1100, MV Agusta Brutale 1090R.
Do not like KTM.
Do not fancy Kawa Z1000.
Did not try GSX-S1000 but I had K5 GSXR1000 before and I have thr new GSXR1000R, so another Gixxer would be one too many.
In any case, of all the nakeds I really only fancy Speed Triple RS, it grabs my soul. S1000R would be second place, it is great in many respects and a great tool, and also cheaper than RS with comparable equipment (heated grips, QS/Blipper, electronic suspension). BMW is also a madder ride...but Speed RS is more my style.
It's just that Daytona is rare and very good, I love it, and it is actually easier to use in filtering through traffic as it is skinnier than Speed RS (it is 100mm wider due to handlebars).
Daytona is also 30kg lighter and razor sharp in corners (sometimes it scares me, especially when I haven't ridden it for a while and then jump on it and go onto our mountain roads), though I do not mind the butch-iness of Speed RS.
It is probably easier to live with Speed RS day-to-day, it is more comfortable, though I do not mind the committed sporty sitting position on Daytona, sportsbikes is the reason I took up motorcycles, I love sportsbikes. Wheelies, knee-down, general hooning is probably easier on Speed RS though.
Even though I do not ride Daytona much (100km in 2018, maybe) I still have separation anxiety. Very hard decision for me. I know, ridiculous first world problem, right?
Ah, also, I would not buy new, I would look for a slightly used Speed RS. There is one with 2000km. New ones, with just a sprinkle of options (heated grips, quickshifter) quickly go into very expensive territory. I can find slightly used and fully equipped (without forged wheels) S1000R for less money, but as I said, it does not tickle my fancy as much as RS.
Cannot sell CBR, noone would want it even for free, it is 2002 model with 60k miles on the clock, all scratched, it's my daily ride and I love it, it fits the bill perfectly, I am not worried about scratches or dirt (it has seen road salt and snow), it is comfortable, easy to filter on it, and fast enough for Swiss roads (I also have 15-47 gearing instead of 16-45, changed fork internals and the damper, put braided lines on it), only up in the mountains above 2000 meters it loses breath noticeably, the old girl.
I know, I had 7 bikes at one time, now paired it down to 4, all sportsbikes (well, I consider F4i a sportsbike), and that is still too many, but I keep them all for different reasons. Daytona, even though I love it, would be the one to sell and replace with RS, the other 3 I keep for now.